Aestivating frogs undergo a profound metabolic depression to functionally extend limited fuel reserves during droughts. The molecular basis of aestivation has not been well established. Here, we will use existing genome-wide gene expression data from the green striped burrowing frog Cyclorana alboguttata to try to understand the role and response of the skeletal musculature to aestivation. The student will be trained in a range of bioinformatics and wet lab molecular tools to turn the enormous volume of mRNA data into convincing explanations of biological processes and biochemical pathways.

Supervisor: Craig Franklin and Nick Hudson

Project members