Integrons are fascinating genetic elements that enable bacteria to capture, store and reshuffle genes, including, most importantly, antibiotic resistance genes.

While quite a bit is known about the molecular biology of integrons, we know very little about their population and evolutionary dynamics.

This project aims to use mathematical models, computer simulations and/or bioinformatics approaches to gain a better understanding for why integrons have evolved and how they help bacteria adapt to their environments.

Supervisor: Dr Jan Engelstaedter