Dr Mazhar Hussain
Postdoctoral Research Fellow
School of Biological Sciences
+61 7 336 52217
Book Chapters
Hussain, M., Etebari, K. and Asgari, S. (2016). Functions of small RNAs in mosquitoes. Progress in Mosquito Research. (pp. 189-222) edited by Alexander S. Raikhel. London, United Kingdom: Academic Press. doi: 10.1016/bs.aiip.2016.04.001
Asgari, Sassan and Hussain, Mazhar (2015). A glance on the role of miRNAs in insect life. Insect molecular biology and ecology. (pp. 121-159) edited by Klaus H. Hoffmann. Boca Raton, Florida United States: CRC Press. doi: 10.1201/b17876
Journal Articles
Hussain, Mazhar, Zhang, Guangmei, Leitner, Michael, Hedges, Lauren M. and Asgari, Sassan (2022). Wolbachia RNase HI contributes to virus blocking in the mosquito Aedes aegypti. iScience, 26 (1) 105836, 105836. doi: 10.1016/j.isci.2022.105836
Hussain, Mazhar, Bradshaw, Twyla, Lee, Morris and Asgari, Sassan (2022). The involvement of atlastin in dengue virus and Wolbachia infection in Aedes aegypti and its regulation by aae-miR-989. Microbiology Spectrum, 10 (5) e0225822, 1-11. doi: 10.1128/spectrum.02258-22
Bishop, Cameron, Hussain, Mazhar, Hugo, Leon E. and Asgari, Sassan (2022). Analysis of Aedes aegypti microRNAs in response to Wolbachia wAlbB infection and their potential role in mosquito longevity. Scientific Reports, 12 (1) 15245, 1-17. doi: 10.1038/s41598-022-19574-x
de Malmanche, Henry, Hussain, Mazhar, Marcellin, Esteban, Reid, Steve and Asgari, Sassan (2022). Knockout of Dicer-2 in the Sf9 cell line enhances the replication of Spodoptera frugiperda rhabdovirus and conditionally increases baculovirus replication. Journal of General Virology, 103 (8) 001779, 1-18. doi: 10.1099/jgv.0.001779
Perdomo, Hugo D., Hussain, Mazhar, Parry, Rhys, Etebari, Kayvan, Hedges, Lauren M., Zhang, Guangmei, Schulz, Benjamin L. and Asgari, Sassan (2021). Human blood microRNA hsa-miR-21-5p induces vitellogenin in the mosquito Aedes aegypti. Communications Biology, 4 (1) 856, 856. doi: 10.1038/s42003-021-02385-7
Asad, Sultan, Hussain, Mazhar, Hugo, Leon, Osei-Amo, Solomon, Zhang, Guangmei, Watterson, Daniel and Asgari, Sassan (2018). Suppression of the pelo protein by Wolbachia and its effect on dengue virus in Aedes aegypti. PLoS Neglected Tropical Diseases, 12 (4) e0006405, e0006405. doi: 10.1371/journal.pntd.0006405
Mehrabadi, Mohammad, Hussain, Mazhar, Matindoost, Leila and Asgari, Sassan (2015). The baculovirus antiapoptotic p35 protein functions as an inhibitor of the host RNA interference antiviral response. Journal of Virology, 89 (16), 8182-8192. doi: 10.1128/JVI.00802-15
Hussain, Mazhar and Asgari, Sassan (2015). Erratum to "microRNAs as mediators of insect host-pathogen interactions and immunity" [Journal of Insect Physiology 70 (2014) 151-158]. Journal of Insect Physiology, 72, 90-90. doi: 10.1016/j.jinsphys.2015.01.010
Mayoral, Jaime G., Hussain, M, Joubertb, D. Albert, Iturbe-Ormaetxe, Iñaki, O'Neill, Scott L. and Asgari, Sassan (2014). Wolbachia small noncoding RNAs and their role in cross-kingdom communications. Proceedings of the National Academy of Science of the United States of America, 111 (52), 18721-18726. doi: 10.1073/pnas.1420131112
Zhang, Guangmei, Hussain, Mazhar and Asgari, Sassan (2014). Regulation of arginine methyltransferase 3 by a Wolbachia-induced microRNA in Aedes aegypti and its effect on Wolbachia and dengue virus replication. Insect Biochemistry and Molecular Biology, 53, 81-88. doi: 10.1016/j.ibmb.2014.08.003
Hussain, Mazhar and Asgari, Sassan (2014). microRNAs as mediators of insect host-pathogen interactions and immunity. Journal of Insect Physiology, 70, 151-158. doi: 10.1016/j.jinsphys.2014.08.003
Slonchak, Andrii, Hussain, Mazhar, Torres Morales, Shessy, Asgari, Sassan and Khromykh, Alexander (2014). Expression of mosquito microRNA aae-miR-2940-5p is down-regulated in response to West Nile Virus infection to restrict viral replication. Journal of Virology, 88 (15), 8457-8467. doi: 10.1128/JVI.00317-14
Hussain, Mazhar and Asgari, Sassan (2014). Reply to Finol: Viral small RNA from Dengue virus and its regulatory role in different serotypes. Proceedings of the National Academy of Sciences of the United States of America, 111 (29), E2917-E2917. doi: 10.1073/pnas.1410765111
Hussain, Mazhar and Asgari, Sasson (2014). Reply to Skalsky et al.: a microRNA-like small RNA from Dengue virus. Proceedings of the National Academy of Sciences, 111 (23), E2360-E2360. doi: 10.1073/pnas.1407176111
Mayoral, Jamie G., Etebari, Kayvan, Hussain, Mazhar, Khromykh, Alexander A. and Asgari, Sassan (2014). Wolbachia infection modifies the profile, shuttling and structure of MicroRNAs in a mosquito cell line. PLoS One, 9 (4) e96107, e96107. doi: 10.1371/journal.pone.0096107
Hussain, Mazhar and Asgari, Sassan (2014). MicroRNA-like viral small RNA from Dengue virus 2 autoregulates its replication in mosquito cells. Proceedings of the National Academy of Sciences, Early Edition (7), 1-6. doi: 10.1073/pnas.1320123111
Hussain, Mazhar, O'Neill, Scott L. and Asgari, Sassan (2013). Wolbachia interferes with the intracellular distribution of Argonaute 1 in the dengue vector Aedes aegypti by manipulating the host microRNAs. RNA Biology, 10 (12), 1868-1875. doi: 10.4161/rna.27392
Jayachandran, Balachandran, Hussain, Mazhar and Asgari, Sassan (2013). Regulation of Helicoverpa armigera ecdysone receptor by miR-14 and its potential link to baculovirus infection. Journal of Invertebrate Pathology, 114 (2), 151-157. doi: 10.1016/j.jip.2013.07.004
Zhang, Guangmei, Hussain, Mazhar, O'Neill, Scott L. and Asgari, Sassan (2013). Wolbachia uses a host microRNA to regulate transcripts of a methyltransferase, contributing to dengue virus inhibition in Aedes aegypti. Proceedings of the National Academy of Sciences of the United States of America, 110 (25), 10276-10281. doi: 10.1073/pnas.1303603110
Mehrabadi, Mohammad, Hussain, Mazhar and Asgari, Sassan (2013). Cloning and characterization of a Dim1-like mitosis gene of Spodoptera frugiperda cells (Sf9) induced by Autographa californica multiple nucleopolyhedrovirus. Journal of Invertebrate Pathology, 113 (2), 152-159. doi: 10.1016/j.jip.2013.02.005
Mehrabadi, Mohammad, Hussain, Mazhar and Asgari, Sassan (2013). MicroRNAome of Spodoptera frugiperda cells (Sf9) and its alteration following baculovirus infection. Journal of General Virology, 94 (Part 6), 1385-1397. doi: 10.1099/vir.0.051060-0
Jayachandran, Balanchandran, Hussain, Mazhar and Asgari, Sassan (2013). An insect trypsin-like serine protease as a target of miRNA: utilization of miRNA mimics and inhibitors by oral feeding. Insect Biochemistry and Molecular Biology, 43 (4), 398-406. doi: 10.1016/j.ibmb.2012.10.004
Etebari, Kayvan, Hussain, Mazhar and Asgari, Sassan (2013). Identification of microRNAs from Plutella xylostella larvae associated with parasitization by Diadegma semiclausum. Insect Biochemistry and Molecular Biology, 43 (4), 309-318. doi: 10.1016/j.ibmb.2013.01.004
Hussain, Mazhar, Walker, Thomas, O'Neill, Scott L. and Asgari, Sassan (2013). Blood meal induced microRNA regulates development and immune associated genes in the Dengue mosquito vector, Aedes aegypti. Insect Biochemistry and Molecular Biology, 43 (2), 146-152. doi: 10.1016/j.ibmb.2012.11.005
Hussain, Mazhar, Lu, Guangjin, Torres, Shessy, Edmonds, Judith H., Kay, Brian H., Khromykh, Alexander A. and Asgari, Sassan (2013). Effect of Wolbachia on replication of West Nile Virus in mosquito cell line and adult mosquitoes. Journal of Virology, 87 (2), 851-858. doi: 10.1128/JVI.01837-12
Jayachandran, Balanchandran, Hussain, Mazhar and Sassan, Asgari (2012). RNA interference as a cellular defense mechanism against the DNA virus, baculovirus. Journal of Virology, 86 (24), 13729-13734. doi: 10.1128/JVI.02041-12
Etebari, Kayvan, Hussain, Mazhar and Asgari, Sassan (2012). Suppression of scavenger receptors transcription by parasitoid factors. Developmental and Comparative Immunology, 38 (4), 517-524. doi: 10.1016/j.dci.2012.08.006
Osei-Amo, Solomon, Hussain, Mazhar, O'Neill, Scott L. and Asgari, Sassan (2012). Wolbachia-induced aae-miR-12 miRNA negatively regulates the expression of MCT1 and MCM6 genes in Wolbachia-infected mosquito cell line. PLoS One, 7 (11) e50049, e50049.1-e50049.8. doi: 10.1371/journal.pone.0050049
Hussain, Mazhar, Torres, Shessy, Schnettler, Esther, Funk, Anneke, Grundhoff, Adam, Pijlman, Gorben P., Khromykh, Alexander A. and Asgari, Sassan (2012). West Nile virus encodes a microRNA-like small RNA in the 3' untranslated region which up-regulates GATA4 mRNA and facilitates virus replication in mosquito cells. Nucleic Acids Research, 40 (5), 2210-2223. doi: 10.1093/nar/gkr848
Hussain, Mazhar, Frentiu, Francesca D., Moreira, Luciano A., O'Neill, Scott L. and Asgari, Sassan (2011). Wolbachia uses host microRNAs to manipulate host gene expression and facilitate colonization of the dengue vector Aedes aegypti. Proceedings of the National Academy of Science of the United States of America - PNAS, 108 (22), 9250-0255. doi: 10.1073/pnas.1105469108
Hussain, Mazher, Abraham, Alexander M. and Asgari, Sassan (2010). An Ascovirus-Encoded RNase III Autoregulates Its Expression and Suppresses RNA Interference-Mediated Gene Silencing. Journal of Virology, 84 (7), 3624-3630. doi: 10.1128/JVI.02362-09
Hussain, Mazher and Asgari, Sassan (2010). Functional analysis of a cellular microRNA in insect host-ascovirus interaction. Journal of Virology, 84 (1), 612-620. doi: 10.1128/JVI.01794-09
Smede, M, Hussain, M and Asgari, S (2009). A lipase-like gene from Heliothis virescens ascovirus (HvAV-3e) is essential for virus replication and cell cleavage. Virus Genes, 39 (3), 409-417. doi: 10.1007/s11262-009-0407-5
Hussain, M, Garrad, S and Asgari, S (2009). The role of actin filaments in ascovirus replication and pathology. Archives of Virology, 154 (11), 1737-1743. doi: 10.1007/s00705-009-0512-8
Hussain, M. and Asgari, S. (2008). Inhibition of apoptosis by Heliothis virescens ascovirus (HvAV-3e): characterization of orf 28 with structural similarity to inhibitor of apoptosis proteins. Apoptosis, 13 (12), 1417-1426. doi: 10.1007/s10495-008-0268-8
Hussain, Mazhar, Taft, Ryan J. and Asgari, Sassan (2008). An insect virus-encoded microRNA regulates viral replication. Journal of Virology, 82 (18), 9164-9170. doi: 10.1128/JVI.01109-08
Thesis
Malik Hussain (2010). ASCOVIRUS INFECTION: Role of microRNAs and viral encoded genes in gene silencing and pathogenesis. PhD Thesis, School of Biological Sciences, The University of Queensland.